POST-TERM PREGNANCY
Definition :
“ A pregnancy continuing beyond 2 weeks of the expected date of delivery (>294 days ) is called post maturity or post-term delivery “
INCIDENCE :
- The incidence of pregnancies continuing beyond 42 completed week (>294 days ) ranges between 4 and 14 %
- The average is about 10%
- Many post term pregnancy are actually wrongly dated
ETIOLOGY :The etiology (causes) of post-term delivery is not fully understood but is thought to involve a combination of factors:
- Unknown Factors :
- In many cases, the exact cause of why some pregnancies go post-term is unknown.
- It could be related to genetic or environmental factors that influence the timing of labor onset.
- Placental Function :
- As the pregnancy progresses beyond term, the placenta may not function as efficiently.
- This could lead to reduced nutrient and oxygen supply to the fetus, prompting the initiation of labor to facilitate delivery.
- Sulfatase deficiency leads to low estrogen
- Maternal Factors :
- Primiparity
- Previous prolonged pregnancy
- older maternal age or obesity.
- Sedentary habit
- These factors can affect hormonal balance and uterine function.
- Fetal Factors :
- Fetal factors, such as genetic predisposition, fetal size, and gender, may also play a role in determining the timing of labor onset.
- Congenital anomalies
- Anencephaly
- Progesterone Withdrawal :
- Towards the end of pregnancy, there is a withdrawal of progesterone and an increase in prostaglandins, which are involved in initiating labor.
- The balance of these hormones may influence the onset of labor.
- Inaccurate Estimation of Gestational Age :
-
Sometimes, errors in estimating the gestational age of the fetus can lead to a misclassification of post-term pregnancy.
- Biological variability ( hereditary ) may be seen in family
- Environmental Factors :
- There is some evidence that environmental factors, such as seasonal variations or sunlight exposure, may influence the timing of labor onset, although the exact mechanisms are not well understood.
INVESTIGATION :